In silico methods – Computational alternatives to animal testing
نویسندگان
چکیده
منابع مشابه
In silico methods - Computational alternatives to animal testing.
ALTEX 35(1), 2018 126 and Refinement of animal testing), their beginnings, impact and development over the years as well as the introduction of additional Rs such as Responsibility, Rehabilitation or Remember. Topics and strategies such as the use of “lower” animals, fewer animals, maximizing study outcome, animal sharing and welfare were discussed. Prof. Schneider closed his talk leading over ...
متن کاملAlternatives in animal testing.
1Division of Hematology/Oncology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 2Division of Cardiology, Department of Medicine, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610, USA 3Department of Pathology, Health Science Center, University of Florida, P.O. Box 100277, Gainesville, FL 32610...
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The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern of ethics, there are few more disadvantage...
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The origins of the concept of alternatives to animal testing in the 1950s, and the range of replacement alternative methods and progress toward their incorporation into fundamental and applied research, education are discussed. The three R’s that is Replacement, Reduction, Refinement are defined. Importance and advantages of alternatives to animal testing methods are mentioned. Information is g...
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Current trends and issues in the development of alternatives to the use of animals in biomedical experimentation are discussed in this position paper. Eight topics are considered and include refinement of acute toxicity assays; eye corrosion/irritation alternatives; skin corrosion/irritation alternatives; contact sensitization alternatives; developmental/reproductive testing alternatives; genet...
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ژورنال
عنوان ژورنال: ALTEX
سال: 2018
ISSN: 1868-596X
DOI: 10.14573/altex.1712031